Are you trying to perform a new fresh installation or upgrading KAV for Lotus to 5.5.1392?
What can you see in the application log file (%TEMP%\kav_lotus.log)?
Please note that this forum is not a Kaspersky technical support forum, it's mostly intended for discussing non-critical issues with community and Kaspersky employees... Please contact tech. support via helpdesk.
Perhaps info in the following page can help, verify the access rights as described there in the Installation section:
http://support.kaspersky.com/faq/?qid=208279408Verify also that your system meets completely system requirements for the application.